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Factors that increase side effect risk While AOD 9604 has a favorable safety profile, certain factors can increase the likelihood or severity of unwanted effects

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However, the largest Phase IIb trial involving 536 participants failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading to development termination in 2007

(PubMed) Watanabe F, Bito T

Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone in vitro and in vivo