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Last Updated: March 27, 2026 Sources of NADPH The reduced form of nicotinamide adenine dinucleotide phosphate (NADPH) is critical to numerous reductive biosynthetic processes such as fatty acid synthesis, cholesterol synthesis, bile acid synthesis, steroid hormone synthesis, and deoxynucleotide synthesis
Excessive ROS may contribute to oxidative injury through alteration of cellular components

Gereben, B
Biochimie 173:100106

This inhibition of pyroptosis in malignant cells is believed to have a significant role in developing HCC [114]
