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However, the binding of any single particular agonist may also initiate activation of multiple different G-proteins, as it may be capable of stabilizing more than one conformation of the GPCR's GEF domain, even over the course of a single interaction

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PubMed Zhang, C., Chopp, M., Cui, Y., Wang, L., Zhang, R., Zhang, L., Lu, M., Szalad, A., Doppler, E., Hitzl, M., & Zhang, Z.G

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