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MI myocardial infarction CVA cerebrovascular accident subjects are selected for treatment who are at risk of future ischemia, but who have no present evidence of ischemia, such as electrocardiographic changes associated with ischemia (for example, peaked or inverted T-waves or ST segment elevations or depression in an appropriate clinical context), elevated CKMB, or clinical evidence of ischemia, including crushing substernal chest pain or arm pain, shortness of breath and/or diaphoresis

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LXR: liver X receptor

Hypoxia-inducible factor-2 mediates the adaptive increase of intestinal ferroportin during iron deficiency in mice

In addition to promoting leukocyte adherence and altering endothelial signal transmission and redox-regulated transcription factors, oxidative stress also raises vascular permeability