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Specifically, iron homeostasis and IL-6 signaling are potential therapeutic targets to mitigate acute liver injury and improve patient outcomes

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Mitochondrial fission and fusion represent a pivotal step in the initiation of mitochondrial autophagy (Zhang et al., 2020)

Furthermore, taking Omenn syndrome as an example, intestinal inflammation can promote the development of skin inflammation by regulating skin chemokines and T cell recruitment, highlighting the important role of the gut-skin axis in inflammatory skin diseases (80)