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Abstract N-methyl-D-aspartate (NMDA) receptors mediate a slow component of excitatory synaptic transmission, are widely distributed throughout the central nervous system, and regulate synaptic plasticity

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For example, Rayner et al

Enzymatic activities such as the abilities of hydrolysis and the transpeptidation of -glutamyl compounds involve amino acid residues located in the large subunit, and therefore, it is very unlikely that these proteins exhibit the same or similar activities compared to those of -glutamyltransferase

Cellular cholesterol homeostasis and Alzheimers disease