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Brain washing and neural health: role of age, sleep, and the cerebrospinal fluid melatonin rhythm
doi: 10.1038/srep33563
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The brain, being highly dependent on glucose and oxygen delivered via cerebral blood flow, becomes especially vulnerable when cerebral blood flow declines due to aging or sleep deprivation, resulting in metabolic instability and overproduction of ROS (Leithner and Royl, 2014
