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Polyphenols as possible alternative agents in chronic fatigue: a review

Ananya Mandal Dr

The efficacy and safety of acetyl-l-carnitine (500 mg three times a day) versus methylcobalamin (0.5 mg three times a day) to treat diabetic peripheral neuropathy was assessed in a Chinese multicentre, randomised, parallel-group, double-blind, double-dummy, positive-controlled, non-inferiority phase II clinical trial

This process, which ensures an adequate supply of free CoA, is essential for the oxidation of pyruvate and helps to coordinate pyruvate dehydrogenase activity with the rate of glycolysis, thereby maintaining the bodys ability to switch between fat and carbohydrate as the main energy substrate [9]