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A comparison of the gut microbiota among adult patients with drug-responsive and drug-resistant epilepsy: an exploratory study

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Mechanistically, HGF-induced synapse formation is mediated by PI-3K and not MAPK activation, as inhibition of the PI-3K/AKT pathway affects synaptogenesis, while blocking MAPK/ERK does not decrease synapse density and only affects dendritic growth (Peng et al., 2016)