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It was described by Hippocrates, who noted its high male-to-female ratio and its association with alcohol

Fluxes and interactions with aspartate aminotransferase and malate/aspartate shuttle

Regarding the effects as you mentioned, digestion etc I didn't feel anything special around those

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However, as noted by Chen and colleagues 52 , this increase in FXR signaling could also be connected to depressive symptoms in FM
