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During this process, tumor cells acquire invasive traits to dissociate from the primary tumor, migrate through surrounding tissues, and colonize distant organsa progression driven by dynamic interactions with immune, stromal, and extracellular matrix components (Zhao et al., 2023)

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Despite the differences in mechanisms and theoretical systems, TCM is relatively more systematic and reproducible, particularly in the standardization of preparations, extraction processes, and compounding theories, which provides a solid foundation for its modernization (Xue et al., 2022