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Some small pilot studies and case reports observe increased endometrial thickness and successful embryo implantation following adjunctive local GHK-Cu administration in assisted reproduction, but sample sizes are small and controls are limited

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These pioneering studies have yielded striking results, indicating that early life treatment with MPH may alter circadian rhythms, induce anxiety that persists into adulthood, and even impair object-recognition memory (Lee et al., 2009