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For patients who experience a sustained increase in resting heart rate while taking semaglutide, the drug should be discontinued

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WHO 2011 guidance on the use of HbA1c in the diagnosis of diabetes mellitus adopted in the UK and reflected in NICE NG28 and NICE diabetes pathways specifies that HbA1c should not be used for diagnosis when conditions affecting red blood cell turnover or haemoglobin are present