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HeNBaiSHuangYXingYChenLYuFet alEvaluation of glutathione S-transferase inhibition effects on idiopathic pulmonary fibrosis therapy with a near-infrared fluorescent probe in cell and mice models

again, oxidative stress is believed to be the culprit, with decreased GSTO gene expression resulting in a lowered age of onset for the diseases

After collection via centrifugation, the cells were incubated in PBS on ice for 10 min

This GSSG compartmentalization may play a role in helping to maintain a reduced cytosolic GSH redox status, implying that plant cells are configured to limit large changes in the cytosolic (and possibly nuclear) GSH redox potentials [46,151,176,177]

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