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Cinciolu-Palabiyik M, et al
doi: 10.1016/j.tips.2018.07.003
The number of senescent cells increases with age, but senescence also plays an important role during development as well as during wound healing
Their effects may be synergic (stimulate growth) or antagonistic as for the effect on glucose metabolism: GH stimulates lipolysis and promotes insulin resistance, whereas IGF-I acts as an insulin agonist
F., Heegaard P
