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2.6 Investigating the mechanism of drug interaction by proteomic and phosphoproteomic analysis To elucidate the synergistic mechanism of our double and triple drug combinations, we examined the proteomics and phosphoproteomics changes in MNA Be(2)-C cells treated with DPI+/-MitoQ+/-Vin for 24 hours by mass spectrometry (MS)
The scientific rationale for studying peptides in this application rests on several converging observations
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