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4-Hydroxynonenal and Ppar ligands affect proliferation, differentiation, and apoptosis in colon cancer cells

Compounding this issue is the lack of validated pharmacodynamic biomarkers that directly link OSC exposure to antimicrobial efficacy in humans
Excess glucose in the body can also react spontaneously with the amino groups of plasma proteins, forming Schiff bases that subsequently contribute to the formation of AGEs [50]

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