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Description
Subsequently, multiple pro-fibrotic factors (e.g., chemokines, proteases, and TGF-) are released, leading to the transition of AEC-II into a mesenchymal phenotype through the process of epithelial-mesenchymal transition (EMT), ultimately resulting in basement membrane destruction [8, 37]
C5aR1 is a master regulator in colorectal tumorigenesis via immune modulation
Not evaluated or approved by the TGA
IL-4 and IL-13 activate tissue-repair macrophages and initiate tissue regeneration (36)
298 The JAK/STAT signaling pathway The signal transducer and activator of transcription (STAT) signaling pathway is involved in the control of vital biological processes such as cell growth, differentiation and the immune response
