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They consist of precipitates of denatured hemoglobin and are the vivid manifestation of the oxidative insult that this protein and the cell itself has experienced

Nature Neuroscience, 5, 301307

Increased GSH levels and GCLC transcription and mRNA levels (GCLM expression was unchanged) also occur in human hepatocellular carcinoma (HCC) [26]

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Lactate dehydrogenase (LDH) release and ATP levels confirmed these protective effects, showing a reduction in LDH release from 212.29% to 122.98% and restoring mitochondrial membrane potential to 94.62% at 50 M of the puerarin-loaded PLGA nanoparticles
