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While these treatments help to relieve the motor symptoms of PD, they do not provide neuroprotection, cannot halt or slow disease progression nor reverse neurodegeneration 6

With the exceptions of exotoxins secreted by enteropathogenic bacteria, such as the clostridial exotoxins or botulinum exotoxins discussed below, most endotoxins of commensal bacteria are not absorbed by the intact intestine of healthy individuals [49, 55]

Additionally, it is necessary to strengthen high-quality clinical research, promote standardization and modernization, explore the precise treatment model integrating disease and syndrome differentiation, and, through in-depth interdisciplinary integration, innovate new drug research, promote the modernization of traditional Chinese medicines, and accelerate clinical translation to provide new progress and breakthroughs for the treatment of RF

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Guo Q, et al