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The antioxidant properties of lipoic acid come from its ability to directly scavenge ROS, its metal-chelating activity, and its potential to react with and promote regeneration of other antioxidants such as glutathione and vitamins E and C

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Intravenous administration of trans-resveratrol-loaded TPGS-coated solid lipid nanoparticles for prolonged systemic circulation, passive brain targeting and improved in vitro cytotoxicity against C6 glioma cell lines

It is FDA-approved as Mounjaro (type 2 diabetes, 2022) and Zepbound (obesity, 2023)