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Liraglutide vs insulin glargine and placebo in combination with metformin and sulfonylurea therapy in type 2 diabetes mellitus (LEAD5 met+SU): a randomised controlled trial

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Stabilisatie van de bloedsuikerspiegel door het verhogen van hormonen zoals GLP-1, glucagon en insuline

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3 Discussion Eighty-two participants, who continued with 14 mg oral semaglutide (the highest dose registered for managing type 2 diabetes) for one year experienced a significant average weight loss of 5.7% (5.9 kg), along with a reduction in BMI by an average of 2 kg/m