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Description

Ideally, the targeted receptor- or carrier-mediated transport processes for brain targeting should occur exclusively at the BBB to avoid off-target delivery

Future research should prioritize elucidating the specific molecular mechanisms underpinning TCM-mediated intestinal barrier regulation and strengthening clinical validation, ultimately advancing the scientific foundation for TCM-based NAFLD therapeutics

From rate-limiting enzyme to therapeutic target: the promise of NAMPT in neurodegenerative diseases

Glutamate is the major excitatory neurotransmitter in the CNS and is involved in mechanisms of activity-dependent synaptic plasticity underlying learning and memory processes, such as long-term potentiation (LTP) and long-term depression (LTD) [108]