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Cognitive and behavioral problems might also manifest

You should not take this medication if you: Are allergic to cyclobenzaprine or any ingredient in the medication Currently, take an MAOI (wait at least 14 days after stopping an MAOI before taking cyclobenzaprine Have recently had a heart attack Have certain heart or heart rhythm conditions, such as heart block or congestive heart failure Have an overactive thyroid (hyperthyroidism) Cyclobenzaprine may be prescribed with caution and close monitoring in individuals with certain medical conditions, such as liver disease, glaucoma, or bladder problems

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Shepherd says

Additional clinical variables such as chronic kidney disease that could confound healing outcomes were also excluded to create a more homogeneous cohort