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The mechanistic link to ECM modulation and gene activation may make it relevant for appendage-regeneration research in dermatology

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Monothiol deglutathionylation mechanisms include CPYC-dependent reactions involving only the active site Cys that is closer to the N-terminus, as well as deglutathionylation via a poplar GRX with a CSYS active site (Couturier et al., 2009)