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Edwards, IR, Aronson, JK

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We will examine the consequences of mtDNA dysfunction for immune cell fate and systemic inflammation, discuss the clinical relevance of mtDNA as a biomarker for toxicity and disease progression, and highlight emerging therapeutic strategies aimed at preserving mitochondrial health to improve the long-term well-being of PLWH

(108), who utilized a porcine cartilage bioassay and demonstrated that glucocorticoid treatment in children decreased IGF-I activity