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Xing L, Shieh HS, Selness SR, Devraj RV, Walker JK, Devadas B, et al

Behav Genet 32:363388

has in fact identified the AGEs as a risk factor for insulin resistance independent of over-nutrition in non-obese mice [53], with such insulin resistance that occurred before changes in blood glucose levels

Consistent with these results, another study on BMAT responses to high-calorie feeding and fasting in healthy humans reported a positive correlation between longitudinal changes in FGF21 and BMAT (153)
