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References Witschi A, Reddy S, Stofer B, Lauterburg BH

This is one reason most IGF-1 LR3 protocols avoid late-evening dosing dosing close to bedtime is more likely to coincide with the natural overnight GH pulse

10.1016/j.jgr.2021.03.003 75 ZhangL.GaoX.YangC.LiangZ.GuanD.YuanT.et al (2024)
Research has demonstrated higher 8-OHdG levels in CSF of non-demented PD patients than those in normal participants (Loeffler et al., 2017)
Clinical and experimental pediatrics