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Purity grade matters significantly for GI and neural research designs because copper-contaminated or low-purity batches introduce confounding variables that make mechanistic interpretation unreliable

Human immunodeficiency virus (HIV)-infected cell death could be triggered by a variety of PCD pathways, including apoptosis, pyroptosis, and ferroptosis ( + T cell line for infecting HIV, + T cell death through apoptosis and pyroptosis in CD4 + T cells (especially in p24 + cells) and ferroptotic cell death (especially in p24 - cells) in the initial phase of infection

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We have shown that the mtDNA-induced cGAS activation in the striatum leads to a robust type I interferon response, exacerbating neuroinflammation and accelerating neurodegeneration

10.3389/fendo.2022.989305 27 ChenY.ZouH.LuH.XiangH.ChenS