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128 This overlap of GI and brain symptoms is commonly present in patients with stress-associated conditions such as dysmotility and inflammation in irritable bowel syndrome (IBS) 244 as well as mental illnesses such as anxiety

Scientific reviews show a compelling mechanistic story supported almost entirely by animal data (Park, 2025)

ImranMAlmehmadiMAlsaiariAAKamalMAlshammariMKAlzahraniMOet al

Timing Your Intake for Success If you are not prepared to part with your morning latte, the solution lies in your schedule

The TCA cycle dynamics seemed to be time-dependent, with an apparent activation at 48 h preferentially supported by anaplerotic aromatic amino acids, leucine and lysine