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t-Darpp activates IGF-1R/AKT signaling through heterodimerization with EGFR and HER2, promoting and stimulating glucose uptake, glycolysis and trastuzumab resistance in SK-BR-3 cells
Masilamoni G, Bogenpohl JW, Alagille D, Delevich K, Tamagnan G, Votaw JR et al (2011)
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A 2015 study in Alcohol and Alcoholism measured glutathione depletion in healthy adults after consuming 1.5g ethanol per kilogram of body weight (roughly 810 standard drinks for a 70kg person)
For those without malabsorption issues, oral B12 supplements may be appropriate if dietary intake is insufficient
