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For instance, depletion of plasmalogen PCs and PUFA-containing GPLs in LID suggests a role in increased membrane fluidity and oxidative vulnerability, whereas the imbalance in hydroxylated and non-hydroxylated sulfatides points to potential disruptions in myelin integrity and neuronal signalling

We first sought to evaluate the internal validity of our dataset

Optical fiber implantation was subsequently conducted, and the complete surgical procedure lasted approximately 11.5 h per mouse

However, further studies, including cytokine profiling and analysis of inflammatory mediators are necessary to confirm this hypothesis
