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One of the most critical yet overlooked biochemical pathways is methylation, a process that affects detoxification, DNA repair, immune function, neurotransmitter balance, fertility and cardiovascular health. Central to the methylation process is the MTHFR (methylenetetrahydrofolate reductase) enzyme, which plays a []

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After inducing ischemic AKI in 810-week-old, male C57BL/6 mice, mass spectrometry metabolomics revealed that the liver had the most distinct phenotype 24 h after AKI versus 4 h and 7 days