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Using the selection of UPR-regulated mRNAs in Figure 1A as a broad indicator of ER stress signaling, we found that etomoxir also diminished UPR activation in C2C12 myoblasts (Figure 1D), and immortalized (data not shown) and primary (Figure 1E) brown adipocytes

Enteric nervous system-derived IL-18 orchestrates mucosal barrier immunity
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[DOI] [PubMed] [Google Scholar] Pandya A, Berneburg M, Ortonne JP, Picardo M

These findings suggest that activating AMPK decreased hippocampal ferroptosis and enhanced cognitive function in diabetic mice [157]

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