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Abstract Phosphonates, often used as isosteric replacements for phosphates, can provide important interactions with an enzyme

8g) shows that the backbone atoms in the CME_c binding mode are relatively stable for the first 300 ns, with deviations around 320 ns and 430 ns

This support is particularly important during periods of stress, illness, or aging, when immune efficiency tends to decline

Among them, CINC-3 exhibits pronounced pro-inflammatory properties within the nervous system, and its expression level correlates tightly with the magnitude of neutrophil infiltration 32,33

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