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Short-term IP exposure engaged cellular repair and stress response pathways, including DNA repair, E2F signaling, p53 pathways, oxidative phosphorylation, and NF-B-associated inflammation in females, features consistent with canonical responses to metabolic stress or tissue injury [4,24]

In 3xTg-AD neurons, rapamycin failed to affect free GTP levels, either because it was unable to stimulate autophagy or that the cells were able to handle the extra load and maintained GTP levels (Fig

however, hyper-reactive inhibitory pathways cause immune exhaustion and paresis

Liu Z, Ye L, Xi J, Wang J

10.2147/ijn.s216972 57 El-ReadiM
