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In vitro experiments confirmed that SPY1 overexpression significantly activated the GCH1/BH4 signaling pathway in NSC-34 cells transfected with the human SOD1 G93A gene
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Alignment of hNET between states of apo (cyan) and MIBG-binding (light blue), RMSD = 0.963

The child's guardian was given the CRWP or the placebo randomized in powder form at two different visits

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