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FIGURE 2 Causes of B12 deficiency and criteria for diagnosis The absorption and metabolic pathway for B12 is highly complex, and defects in any part of this process can lead to therapeutic B12 replacement

Acs Sensors 2 , 12571261, (2017)

Parallel genomic alterations of antigen and payload targets mediate polyclonal acquired clinical resistance to sacituzumab govitecan in triple-negative breast cancer

The second problem is that reference ranges are quite broad and based on the current, generally healthy population, not an optimally healthy population

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