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Description
Transcriptional up-regulation of -glutamylcysteine synthetase gene expression in melphalan-resistant human prostate carcinoma cells
It acts as a cofactor for methionine synthase and methylmalonyl-CoA mutase, enzymes that are critical for one-carbon metabolism as well as the catabolism of odd-chain fatty acids and branched-chain amino acids (Rucker et al., 2007)
PROTACs: great opportunities for academia and industry (an update from 2020 to 2021)
Li W, Khor TO, Xu C, Shen G, Jeong WS, et al
doi: 10.1002/jmv.26716
