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The oral mucosa covers approximately 170 cm 2 , plays a critical role in drug delivery in the mouth, with its structure and properties at given sites influencing the absorption and effectiveness of medications [35]
Paraesthesia (pins and needles) in the hands and feet often improves within two to four weeks, though complete resolution may take several months
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Various studies have reported that overexpression or amplification of c-Met in early (I and II) and late CRC (III and IV) is closely related to its invasion and distant metastasis (Zeng et al., 2008
