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This approach mitigated inherent instrument fluctuations over an extended period ( Data processing and statistical analysis Lipid annotation was conducted by LipidSearch 4.0 (Thermo Scientific), based on the precursor ion and MS/MS fragmented ions with mass accuracy error 1, P 0.35 were considered to have a significant association with RA disease activity

The study was conducted according to Helsinki principles, declared to the Commission Nationale de lInformatique et des Liberts (declaration number, 2067659) and approved by the ethics committee of the French Society of Intensive Care (protocol number, FICS20020231)

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Lipid-lowering nutraceuticals in clinical practice: position paper from an international lipid expert panel