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J Chem Neuroanat 102:101706 Maksoud R, Balinas C, Holden S et al (2021) A systematic review of nutraceutical interventions for mitochondrial dysfunctions in myalgic encephalomyelitis/chronic fatigue syndrome

Choline complements this by serving as a precursor for acetylcholine synthesis and supporting VLDL assembly independently of the methionine-SAMe pathway

( 10.1080/16512235.2017.1327309) [DOI] [PMC free article] [PubMed] [Google Scholar] 61

Together, these features make the db/db mice an attractive model for studying pathogenic mechanisms of HFpEF