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Some variants are assigned as P/LP based on classification as high prediction of loss-of-function based on protein effects (e.g., nonsense, frameshift, large deletions, etc.)

10.1016/j.phymed.2021.153662 97 LiD.KeY.ZhanR.LiuC.ZhaoM.ZengA.et al (2018)

L-Carnitin ist eine natrlich vorkommende Verbindung, die im menschlichen Krper gebildet wird und auerdem ber verschiedene Lebensmittel aufgenommen werden kann

( 10.1097/01.gco.0000192994.37965.c6) [DOI] [PubMed] [Google Scholar] Tsounapi P, Honda M, Dimitriadis F, Koukos S, Hikita K, Zachariou A, Sofikitis N, Takenaka A.2018

L-carnitine and renal insufficiency (kidney failure) The carnitine homeostasis (balance within the body) can be significantly impaired in people with a kidney disease due to several factors