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Chemotherapy activates the DDR pathway

Niacin-supplemented AD mice also had elevated expression of genes including Ctnnb1 , Mdm2 , and Pten , which are involved in processes such as Wnt signalling, posttranslational modifications, and regulation of mTOR signalling [155]

ER, endoplasmic reticulum

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Simultaneously, they arent absorbing vitamin B12 well because of changes to their digestive tract
