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Mitochondria are involved in the RCD process of apoptosis, which indicates that NiO NPs can induce apoptosis in yeast which is dependent on caspase and mitochondria
Armstrong, J

Furthermore, oxidative stress can impede the nucleoplasmic translocation of pancreaticoduodenal homeobox factor 1 (PDX-1), impair energy metabolism, and reduce insulin production and release (Duni et al., 2019)
Conclusion This review highlights the potential of natural anti-cancer products derived from herbal medicine, underscoring their diverse pharmacological properties and mechanisms of action

& Bertino, J
