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Nevertheless, the long-term efficacy and safety of these drugs need further validation

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Lastly, although the hangover symptom surveys (AHS and AHSS) showed no significant differences between the GSH and placebo groups overall, the subjective nature of these surveys may have influenced the results

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doi: 10.1046/j.1471-4159.2001.00310.x

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NCOA4-mediated promotion mechanism NCOA4 is important in various cellular processes, surpassing its originally identified role as a coactivator for nuclear receptors, such as androgen and thyroid hormone receptors (74,75)

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