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(Source 7, 8) The disease can be mild, moderate, or severe, and symptoms include: Hemolytic anemia (a rare anemia caused by the breakdown of red blood cells) Metabolic acidosis (acid buildup) Recurrent bacterial infections Seizures Intellectual disability Ataxia (loss of coordination) (Source 6) Supplementation to Raise Glutathione Concentrations Dietary strategies support the prevention of glutathione depletion

Transketolase is encoded by the TKT gene

Taken as a daily oral capsule

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Supplement with other minerals and vitamins if youre low in them, so that you dont confuse their deficiency symptoms with reactions from the B12 supplement