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Low levels of ERK phosphorylation were also observed [65,66]

(2002) Protein misfolding in Alzheimers and Parkinsons disease: genetics and molecular mechanisms

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The IGF Signaling Axis The insulin-like growth factors (IGFs) belong to the insulin and IGF signaling (IIS) pathway, which is comprised of a network of ligands, receptors, and binding proteins that mediate signaling to control and coordinate normal organismal growth and metabolism (Figure 1)

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