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Muscle soreness that lingers beyond a normal window

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Another difference is in how quickly these symptoms appear and evolve

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According to the study of Chen, IncRNA NEAT1 induces sorafenib resistance of HCC patients through repressing miR-335 expression and activation of c-Met-Akt signaling pathway (Shao et al., 2015) and the combination of HGF and c-Met inhibitors and sorefenib could improve the efficacy of the first line systemic treatment ( In conclusion, although the tivantinib phase III trial failed and the reason is not clear, the role of c-Met inhibitors in treating HCC can not be denied

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In addition, another female subject dropped out just before the final 5-km time trial because she was pregnant

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Virulence 4 , 185191 (2013)

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