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In this context, ferroptosis exerts a context-dependent double-edged sword effect [127]: while targeted induction of ferroptosis in hyperproliferative PASMCs could theoretically reverse remodeling, uncontrolled ferroptosis leads to deleterious vascular injury [128, 129]

The Dihydroethidium (DHE) fluorescent probe was purchased from Yisheng Biotechnology (Shanghai) Co., Ltd

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However, the efficacy of rhamnetin in less-studied cancers, including pancreatic and oesophageal cancers, requires further validation to determine its broader applicability

Are there any side effects to taking NAC or glutathione